DMEK, Descemet Membrane Endothelial Keratoplasty, is a similar procedure to DSAEK. There are however a few small differences. The first difference is that in DMEK only the very thin membrane holding the endothelial cells is transplanted, without any additional corneal tissue. This makes the DMEK tissue a little more challenging to manipulate within the eye. The second difference is that a longer lasting gas (SF6) is used to hold the transplanted tissue to the recipient cornea. It can take two to three weeks to determine if the transplanted tissue will remain fully adherent and not require additional manipulation. DMEK is ideal for younger patient’s with endothelial dysfunction causing a reduction in their vision.